Training the next generation of virologists
Biography Professor of Oncology and Medicine, Wattawa Professor in Cancer Research Dr. Kenney’s research is focused on understanding the molecular regulation and pathogenesis of Epstein-Barr virus (EBV), and developing humanized mouse models to dissect how EBV causes B-cell lymphomas in vivo. Her work in EBV spans a broad range of topics, including viral gene regulation, …
Biography Associate Professor of Human Oncology The ultimate goal of the Kimple lab is to improve treatment outcomes for cancer patients. They pursue this goal by studying the molecular mechanisms leading to increased sensitivity to therapy in HPV-positive cancers and studying how to target therapeutic resistance in head and neck cancer. Alex Torres Law, a …
Biography John E. Butler Professor of Comparative and Mucosal Immunology The overall goal of Dr. Suresh’s research is to use a multidisciplinary approach to decipher the cellular and molecular basis of T cell immunity to mucosal and systemic viral infections. First, by defining the tenets of programming long-term T cell immunity in the mucosal tissues, …
Biography Associate Professor of Medical Microbiology and Immunology Humans are under continual assault by seasonal influenza virus outbreaks as well as sporadic pandemics. Like all viruses, influenza virus is completely dependent upon the host cell for replication. Influenza virus exploits and subverts host processes while at the same time evading cellular antiviral responses. The balance between these pro- and …
Biography Elizabeth McCoy Professor of Oncology Dr. Mertz has continued her studies aimed at understanding regulation of the switch between Epstein-Barr virus (EBV) latency and lytic replication in epithelial and B cells by a variety of cellular and virus-encoded proteins and physiological inducers such as TGF-β and hypoxia. They have identified several cis-acting elements and …
Biography UW Medical Foundation Professor of Pathology and Laboratory Medicine Dr. David O’Connor’s laboratory studies virus-host interactions, with an emphasis on RNA viruses. His laboratory currently has 6 major, overlapping research areas: simian arteriviruses pathogenesis; host genomics; HIV/SIV pathogenesis; viral immunology; immunomodulation by pegiviruses; and understanding congenital Zika virus. In the last five years, they …
Biography Associate Professor, Department of Pathology and Laboratory Medicine Dr. Shelby O’Connor is interested in understanding host immune responses to SIV and the effect that a pre-existing SIV-infection has on host immunity to other pathogens. Her laboratory uses nonhuman primates with defined host MHC genetics to understand key factors of immunity against SIV, a virus …
Biography Professor of Biochemistry and Institute for Molecular Virology Dr. Ann Palmenberg’s research program investigates multiple aspects of RNA virology and bioinformatics methods for viral genomics. Among her major research goals are to explore and define the relationship of the cardiovirus genus to other members of the picornavirus family and to exploit the unique features …
Biography Assistant Professor of Plant Pathology The discovery of internal ribosome entry site (IRES) elements in certain RNA messages uncovered a pivotal mechanism of translational regulation in virus infection and in many physiological and pathological stress conditions in eukaryotic cells. Studies of animal viruses have provided major insights into IRES sequences, structures, requirements for host …