People Type: Predoctoral Trainee

Biography Research Title.  Phospho-Regulation of the Influenza Virus Replication Machinery. Research Description. Influenza viruses are the etiological agents for seasonal influenza outbreaks and sporadic influenza pandemics in both human and avian populations, resulting in high public health and economic burdens worldwide. The success of these viruses requires host factors to regulate both cellular and viral …

Biography Research Title: Defining Shared and Distinct Anti-Viral Antibody Responses and Discerning How these Responses Contribute to Protection or to Pathology Research Description:  To date, immunological interactions between heterologous members of the family Flaviviridae, a group of viruses with significant public health impacts, are not well understood. Anna Heffron’s research focuses on deepening our mechanistic …

Biography Research Title.  Gene Correlation Analysis Identifies Functional Pro- and Anti-Viral Factors for Influenza Virus Infection. Research Description. Influenza A virus (IAV), like all viruses, must co-opt host cellular machinery to support successful infection. Gloria’s research uses an unbiased genetic screen to identify host factors that regulate IAV infection. Top candidates included the potential antiviral …

Biography Research Title:  Determining the Role of Hepatitis B Virus Viral Proteins, Core and P, in cccDNA Persistence and Genome Maintenance Research Description: Although the discovery of a vaccine against Hepatitis B virus has contributed to a steady decline in the number of cases since the 1980’s. Unfortunately, an estimate 800,000 deaths occurred in 2015 …

Biography Research Title.  Regulation of EBV Lytic Reactivation by p53 and p63 in Epithelial Cells. Research Description.  Epstein Barr virus (EBV) is a ubiquitous viral infection that persists in the majority of adults. While many infected individuals will not experience symptoms after primary infection, EBV is responsible for ~2% of cancers globally. EBV is associated …